Changzhi Sanbao Biochemical Pharmaceutical Co., Ltd.  

Product Name: Acetylcysteine Western Medicine Glutathione Whit Skin Model NO.: injection Pharmaceutical Technology: Chemical Synthesis Type: Inorganic Chemicals Shape: Injection State: Liquid Suitable for: Elderly, Adult Usage Mode: For external use Application: Internal Medicine Trademark: dscbueat Transport Package: Box Specification: amps Origin: China Product Description Acetylcysteine serves as aprodrug to L-cysteine.L-cysteine is aprecursor to the biologic antioxidant glutathione. Hence administration of acetylcysteine replenishes glutathione stores.- Glutathione, along with oxidized glutathione (GSSG) and S-nitrosoglutathione (GSNO), have been found to bind to the glutamate recognition site of the NMDA and AMPA receptors (via their γ-glutamyl moieties), and may be endogenous neuromodulators.] At millimolar concentrations, they may also modulate the redox state of the NMDA receptor complex. In addition, glutathione has been found to bind to and activate ionotropic receptors that are different from any other excitatory amino acid receptor, and which may constitute glutathione receptors, potentially making it aneurotransmitter. As such, since N-acetylcysteine is aprodrug of glutathione, it may modulate all of the aforementioned receptors as well.- Glutathione also modulates the NMDA receptor by acting at the redox site.L-cysteine also serves as aprecursor to cystine which in turn serves as asubstrate for the cystine-glutamate antiporter on astrocytes hence increasing glutamate release into the extracellular space. This glutamate in turn acts on mGluR2/3 receptors, and at higher doses of acetylcysteine, mGluR5.Acetylcysteine also possesses some anti-inflammatory effects possibly via inhibiting NF-κB and modulating cytokine synthesis.Tel.:+86 021 50902161Fax:+86 021 50903907Mobile: +86 15500256655